Volume 104, Issue 6 pp. 1544-1559
Review Article

Suture materials — Current and emerging trends

Christopher Dennis

Christopher Dennis

Centre for Biomaterials Science and Technology, School of Mechanical and Building Sciences, VIT University, Vellore, Tamil Nadu, 632014 India

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Swaminathan Sethu

Swaminathan Sethu

GROW Research Laboratory, Narayana Nethralaya Foundation, Bangalore, Karnataka, 560099 India

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Sunita Nayak

Sunita Nayak

Centre for Biomaterials Science and Technology, School of Mechanical and Building Sciences, VIT University, Vellore, Tamil Nadu, 632014 India

School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, 632014 India

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Loganathan Mohan

Loganathan Mohan

Surface Engineering Division, CSIR - National Aerospace Laboratories, Bangalore, Karnataka, 560017 India

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Yosry (Yos) Morsi

Yosry (Yos) Morsi

Biomechanical and Tissue Engineering Labs, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Australia

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Geetha Manivasagam

Corresponding Author

Geetha Manivasagam

Centre for Biomaterials Science and Technology, School of Mechanical and Building Sciences, VIT University, Vellore, Tamil Nadu, 632014 India

Correspondence to: G. Manivasagam; e-mail: [email protected]Search for more papers by this author
First published: 10 February 2016
Citations: 149

Abstract

Surgical sutures are used to facilitate closure and healing of surgical- or trauma-induced wounds by upholding tissues together to facilitate healing process. There is a wide range of suture materials for medical purpose and the main types include absorbable and nonabsorbable. Recently, there is a growth in the development of classes of suture materials based on their properties and capabilities to improve tissue approximation and wound closure. This review outlines and discusses the current and emerging trends in suture technology including knotless barbed sutures, antimicrobial sutures, bio-active sutures such as drug-eluting and stem cells seeded sutures, and smart sutures including elastic, and electronic sutures. These newer strategies expand the versatility of sutures from being used as just a physical entity approximating opposing tissues to a more biologically active component enabling delivery of drugs and cells to the desired site with immense application potential in both therapeutics and diagnostics. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 1544–1559, 2016.

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