Case Report
Steroid-Resistant Idiopathic Esophageal Ulcer in a Child with AIDS
Rima M. Jibaly,
Hamid Moallem,
Senih M. Fikrig,
Simon S. Rabinowitz,
Rima M. Jibaly
SUNY Health Science Center Brooklyn, Department of Pediatrics, Brooklyn, New York, U.S.A.
Search for more papers by this authorHamid Moallem
SUNY Health Science Center Brooklyn, Department of Pediatrics, Brooklyn, New York, U.S.A.
Search for more papers by this authorSenih M. Fikrig
SUNY Health Science Center Brooklyn, Department of Pediatrics, Brooklyn, New York, U.S.A.
Search for more papers by this authorCorresponding Author
Simon S. Rabinowitz
SUNY Health Science Center Brooklyn, Department of Pediatrics, Brooklyn, New York, U.S.A.
Address correspondence and reprint requests to Dr. S. S. Rabinowitz, SUNY Health Science Center Brooklyn, Department of Pediatrics, Box 49, 450 Clarkson Avenue, Brooklyn, NY 11203, U.S.A.Search for more papers by this authorRima M. Jibaly,
Hamid Moallem,
Senih M. Fikrig,
Simon S. Rabinowitz,
Rima M. Jibaly
SUNY Health Science Center Brooklyn, Department of Pediatrics, Brooklyn, New York, U.S.A.
Search for more papers by this authorHamid Moallem
SUNY Health Science Center Brooklyn, Department of Pediatrics, Brooklyn, New York, U.S.A.
Search for more papers by this authorSenih M. Fikrig
SUNY Health Science Center Brooklyn, Department of Pediatrics, Brooklyn, New York, U.S.A.
Search for more papers by this authorCorresponding Author
Simon S. Rabinowitz
SUNY Health Science Center Brooklyn, Department of Pediatrics, Brooklyn, New York, U.S.A.
Address correspondence and reprint requests to Dr. S. S. Rabinowitz, SUNY Health Science Center Brooklyn, Department of Pediatrics, Box 49, 450 Clarkson Avenue, Brooklyn, NY 11203, U.S.A.Search for more papers by this authorFirst published: 01 July 1998
No abstract is available for this article.
REFERENCES
- 1Wilcox CM, Schwartz DA, Clark WS. Esophageal ulceration in human immunodeficiency virus infection. Ann Int Med 1995; 123: 143–9.
- 2Sor S, Levine MS, Kowalski TE, Laufer I, Rubesin SE, Herlinger H. Giant ulcers of the esophagus in patients with human immunodeficiency virus: Clinical, radiographic and pathologic findings. Radiology 1995; 194: 447–51.
- 3Martinez EJ, Nord JH, Cooper BG. Significance of solitary and multiple esophageal ulcers in patients with AIDS. South Med J 1995; 88: 626–9.
- 4Kotler DP, Reka S, Orenstein JM, Fox CH. Chronic idiopathic esophageal ulceration in the acquired immunodeficiency syndrome. characterization and treatment with corticosteriods. J Clin Gastroenterol 1992; 15: 284–90.
- 5Wilcox CM, Straub RF, Schwartz DA. Prospective endoscopic characterization of cytomegalovirus esophagitis in AIDS. Gastrointest Endosc 1994; 40: 481–4.
- 6Kitchen VS, Helbert M, Francis ND, et al. Epstein-Barr virus associated esophageal ulcers in AIDS. Gut 1990; 31: 1223–5.
- 7Bonacini M, Young T, Laine L. The causes of esophageal symptoms in human immunodeficiency virus infection. Arch Intern Med 1991; 151: 1567–72.
- 8Chow D, Bleikh S, Eickhoff L, Soloway G, Saul Z. Primary esophageal lymphoma in AIDS presenting as a nonhealing esophageal ulcer. Am J Gastroenterol 1996; 91: 602–3.
- 9Wilcox CM, Schwartz DA. Comparison of two corticosteroid regimens for the treatment of HIV-associated idiopathic esophageal ulcer. Am J Gastroenterol 1994; 89: 2163–7.
- 101994 revised classification system for human immunodeficiency virus infection in children less than 13 years of age. MMWR 1994; 43: 1–19.
- 11Wilcox CM, Schwartz, DA. Endoscopic characterization of idiopathic esophageal ulceration association with human immunodeficiency virus infection. J Clin Gastroenterol 1993; 16: 251–6.
- 12Clarke LM, McPhee JM, Cummings RV. Isolation of viruses in conventional tube culture: Selection and inoculation of cell cultures. In: HD Isenberg, ed. Clinical microbiology procedures handbook. Vol. 2, Sec. 8.5.1-13). American Society for Microbiology: Washington, DC, 1992.
- 13Kotler DP, Wilson CS, Haroutiounian G, Fox CH. Detection of human immunodeficiency virus by 35 S-RNA in situ hybridization in solitary esophageal ulcers in two patients with the acquired immune deficiency syndrome. Am J Gastroenterol 1989; 84: 313–7.
- 14Jalfon IM, Sitton JE, Hammer RA, Agrawal NM, Ertan A, Mahatma M. HIV-1 gp41 antigen demonstration in esophageal ulcers with acquired immunodeficiency syndrome. J Clin Gastroenterol 1991; 13: 644–8.
- 15Chawla S, Ramani K, Chawla K, LoPresti PH, Mahadevia P. Giant esophageal ulcers of AIDS: Ultrastructural study. Am J Gastroenterol 1994; 89: 411–5.
- 16Wilcox CM, Zaki SR, Coffield LM, Greer PW, Schwartz DA. Evaluation of idiopathic esophageal ulceration for human immunodeficiency virus. Mod Pathol 1995; 8: 568–2.
- 17Naum SM, Molloy PJ, Kania RJ, McGarr J, Van Thiel DH. Use of thalidomide in treatment and maintenance of idiopathic esophageal ulcers in HIV+ individuals. Dig Dis Sci 1995; 40: 1147–8.
- 18Paterson DL, Georghiou PR, Allworth AM, Kemp RJ. Thalidomide as treatment of refractory aphthous ulceration related to human immunodeficiency virus infection. Clin Infect Dis 1995; 20: 250–4.
- 19Ghigliotti G, Repetto T, Farris A, Roy M, DeMarch R. Thalidomide for severe aphthous ulceration in patients with human immunodeficiency virus (HIV) infection. J Am Acad Dermatol 1993; 28: 271–2.
- 20Menni S, Imondi D, Brancaleone W, Croci S. Recurrent giant aphthous ulcers in a child: Protracted Treatment with thalidomide. Pediatr Dermatol 1993; 10: 283–5.
- 21Klausner JD, Makonkawkeyoon S, Akarasewi P, et al. The effect of thalidomide on the pathogenesis of human immunodeficiency virus type 1 and M. tuberculosis infection. J Acquir Immune Defic Syndr Hum Retrovirol 1996; 11: 247–57.
- 22Moreira AL, Sampaio EP, Zmuidzinas A, Frindt P, Smith KA, Kaplan G. Thalidomide exerts its inhibitory action on tumor necrosis factor α by enhancing mRNA degradation. J Exp Med 1993; 177: 1675–80.
- 23Rabeneck L, Popovic M, Gartner S, et al. Acute HIV infection presenting with painful swallowing and esophageal ulcers. JAMA 1990; 263: 2318–22.
