Efficient Synthesis of 2-(2-Aminophenyl)-2,3-dihydropyridin-4(1H)-ones Based on a Cyclization/Ring Cleavage Procedure
Vahuni Karapetyan
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Faculty of Chemistry, Yerevan State University, Alex Manoogian 1, 0025 Yerevan, Armenia
Search for more papers by this authorSatenik Mkrtchyan
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Faculty of Chemistry, Yerevan State University, Alex Manoogian 1, 0025 Yerevan, Armenia
Search for more papers by this authorGnuni Karapetyan
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Search for more papers by this authorAlexander Villinger
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Search for more papers by this authorAshot Saghiyan
Faculty of Chemistry, Yerevan State University, Alex Manoogian 1, 0025 Yerevan, Armenia
CJSC Scientific Research Institute of Biotechnology, Gyurjyan Str. 14, 0056, Yerevan, Armenia
Search for more papers by this authorTariel V. Ghochikyan
Faculty of Chemistry, Yerevan State University, Alex Manoogian 1, 0025 Yerevan, Armenia
Search for more papers by this authorCorresponding Author
Peter Langer
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Leibniz -Institut für Katalyse e. V. an der Universität, Rostock, Albert-Einstein-Str. 29a, D-18059 Rostock
Leibniz-Institut für Katalyse e. V. an der Universität, Rostock, Albert-Einstein-Str. 29a, D-18059 RostockSearch for more papers by this authorVahuni Karapetyan
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Faculty of Chemistry, Yerevan State University, Alex Manoogian 1, 0025 Yerevan, Armenia
Search for more papers by this authorSatenik Mkrtchyan
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Faculty of Chemistry, Yerevan State University, Alex Manoogian 1, 0025 Yerevan, Armenia
Search for more papers by this authorGnuni Karapetyan
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Search for more papers by this authorAlexander Villinger
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Search for more papers by this authorAshot Saghiyan
Faculty of Chemistry, Yerevan State University, Alex Manoogian 1, 0025 Yerevan, Armenia
CJSC Scientific Research Institute of Biotechnology, Gyurjyan Str. 14, 0056, Yerevan, Armenia
Search for more papers by this authorTariel V. Ghochikyan
Faculty of Chemistry, Yerevan State University, Alex Manoogian 1, 0025 Yerevan, Armenia
Search for more papers by this authorCorresponding Author
Peter Langer
Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, D-18059 Rostock
Leibniz -Institut für Katalyse e. V. an der Universität, Rostock, Albert-Einstein-Str. 29a, D-18059 Rostock
Leibniz-Institut für Katalyse e. V. an der Universität, Rostock, Albert-Einstein-Str. 29a, D-18059 RostockSearch for more papers by this authorAbstract
(Benzyloxycarbonyl)-protected 3,4-benzo-7-hydroxy-2,9-diazabicyclo[3.3.1]non-7-enes were prepared by one-pot cyclizations of 1,3-bis(silyl enol ethers) with quinazolines. Subsequent hydrogenation resulted in one-pot deprotection and rearrangement to give 2-(2-aminophenyl)-2,3-dihydropyridin-4(1H)-ones.
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