Volume 94, Issue 11 pp. 2020-2026
Research Article

Two New Cryptoporic Acid Derivatives from the Fruiting Bodies of Cryptoporus sinensis

Wen Wu

Wen Wu

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua-Road, Shenyang 110016, P. R. China (phone: +86-024-23986500)

Key Lab of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, No. 8 Beiertiao, Zhongguancun, Haidian District, Beijing 100190, P. R. China, (phone: +86-10-62566577; fax: +86-10-62566511)

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Feng Zhao

Feng Zhao

School of Pharmacy, Yantai University, No. 32 QingQuan Road, Laishan District, Yantai 264005, P. R. China

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Li Bao

Li Bao

Key Lab of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, No. 8 Beiertiao, Zhongguancun, Haidian District, Beijing 100190, P. R. China, (phone: +86-10-62566577; fax: +86-10-62566511)

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Jin-Cai Lu

Corresponding Author

Jin-Cai Lu

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua-Road, Shenyang 110016, P. R. China (phone: +86-024-23986500)

Jin-Cai Lu, College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua-Road, Shenyang 110016, P. R. China (phone: +86-024-23986500)

Hong-Wei Liu, Key Lab of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, No. 8 Beiertiao, Zhongguancun, Haidian District, Beijing 100190, P. R. China, (phone: +86-10-62566577; fax: +86-10-62566511)

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Hong-Wei Liu

Corresponding Author

Hong-Wei Liu

Key Lab of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, No. 8 Beiertiao, Zhongguancun, Haidian District, Beijing 100190, P. R. China, (phone: +86-10-62566577; fax: +86-10-62566511)

Jin-Cai Lu, College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua-Road, Shenyang 110016, P. R. China (phone: +86-024-23986500)

Hong-Wei Liu, Key Lab of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, No. 8 Beiertiao, Zhongguancun, Haidian District, Beijing 100190, P. R. China, (phone: +86-10-62566577; fax: +86-10-62566511)

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First published: 14 November 2011
Citations: 11

Abstract

Two new drimane-type sesquiterpenoid ethers of isocitric acid, cryptoporic acids N (1) and O (6), were isolated from the fruiting bodies of Cryptoporus sinensis. Their structures were established by means of spectroscopic methods, including 1D- and 2D-NMR. The cytotoxic activity against a panel of cell lines (A549, MCF-7, PC-3, and PANC-1) was evaluated for all cryptoporic acid derivatives 112 isolated.

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