Scyphiphorins A and B, Two New Iridoid Glycosides from the Stem Bark of a Chinese Mangrove Scyphiphora hydrophyllacea
Abstract
Two new iridoid glycosides, named scyphiphorins A (1) and B (2), together with four known compounds, geniposidic acid (=(1S,4aS,7aS)-1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid; 3), 4-(4-hydroxy-3-methoxybenzyl)butan-2-one, oleanolic acid (=(3β)-3-hydroxyolean-12-en-28-oic acid), and stigmasterol β-D-glucoside (=(3β,22E)-stigmasta-5,22-dien-3-yl β-D-glucopyranoside), were isolated for the first time from the stem bark of a Chinese mangrove, Scyphiphora hydrophyllacea Gaertn. f. The structures of compounds 1 and 2 were determined as 10-O-benzoylgeniposidic acid and 10-O-[(2E,6R)-8-hydroxy-2,6-dimethyl-1-oxooct-2-en-1-yl]geniposidic acid, respectively, on the basis of spectroscopic data and chemical methods, including 2D NMR techniques.
