Volume 74, Issue 3 pp. 1509-1522
Original Article

Financial Hardship From Medical Bills Among Adults With Chronic Liver Diseases: National Estimates From the United States

Carlos Lago-Hernandez

Carlos Lago-Hernandez

Division of Hospital Medicine, Department of Medicine, University of California, San Diego, La Jolla, CA

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Nghia H. Nguyen

Nghia H. Nguyen

Division of Gastroenterology and Hepatology, Department of Medicine, University of California, San Diego, La Jolla, CA

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Rohan Khera

Rohan Khera

Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT

Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT

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Rohit Loomba

Rohit Loomba

Division of Gastroenterology and Hepatology, Department of Medicine, University of California, San Diego, La Jolla, CA

NAFLD Research Center, Department of Medicine, University of California, San Diego, La Jolla, CA

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Sumeet K. Asrani

Sumeet K. Asrani

Baylor University Medical Center, Dallas, TX

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Siddharth Singh

Corresponding Author

Siddharth Singh

Division of Gastroenterology and Hepatology, Department of Medicine, University of California, San Diego, La Jolla, CA

Division of Biomedical Informatics, Department of Medicine, University of California, San Diego, La Jolla, CA

ADDRESS CORRESPONDENCE AND REPRINT REQUESTS TO:

Siddharth Singh, M.D., M.S.

Divisions of Gastroenterology and Biomedical Informatics, Department of Medicine, University of California, San Diego

9452 Medical Center Drive

ACTRI 1W501

La Jolla, CA 92093

E-mail: [email protected]

Tel.: +1-858-246-2352

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First published: 26 March 2021
Citations: 4
Supported by the National Institutes of Health (NIH)/National Institute of Diabetes and Digestive and Kidney Diseases (T32DK007202 to N.H.N. and K23DK117058 to S.S.), NIH/National Library of Medicine (T15LM011271 to N.H.N.), and the American College of Gastroenterology Junior Faculty Development Award (144271 to S.S.).
Potential conflict of interest: Dr. Loomba consults and received grants from AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Galmed, Gilead, Intercept, Janssen, Madrigal, NGM, and Pfizer. He consults for Alnylam/Regeneron, Amgen, Arrowhead, CohBar, Glympse, Inipharm, Ionis, Metacrine, Novartis, Novo Nordisk, Sagiment, 89 Bio, and Viking. He received grants from Allergan, Boehringer-Ingelheim, Galectin, Genfit, Inventiva, Merck, and Siemens.

Abstract

Background and Aims

Chronic liver diseases (CLD) affect approximately 2% of the U.S. population and are associated with substantial burden of hospitalization and costs. We estimated the national burden and consequences of financial hardship from medical bills in individuals with CLD.

Approach and Results

Using the National Health Interview Survey from 2014 to 2018, we identified individuals with self-reported CLD. We used complex weighted survey analysis to obtain national estimates of financial hardship from medical bills and other financial toxicity measures (eg, cost-related medication nonadherence, personal and/or health care–related financial distress, food insecurity). We evaluated the association of financial hardship from medical bills with unplanned health care use and work productivity, accounting for differences in age, sex, race/ethnicity, insurance, income, education, and comorbidities. Of the 3,666 (representing 5.3 million) U.S. adults with CLD, 1,377 (representing 2 million [37%, 95% CI: 35%-39%]) reported financial hardship from medical bills, including 549 (representing 740,000 [14%, 95% CI: 13%-16%]) who were unable to pay medical bills at all. Adults who were unable to pay medical bills had 8.4-times higher odds of cost-related medication nonadherence (adjusted OR [aOR], 8.39 [95% CI, 5.72-12.32]), 6.3-times higher odds of financial distress (aOR, 6.33 [4.44-9.03]), and 5.6-times higher odds of food insecurity (aOR, 5.59 [3.74-8.37]), as compared to patients without financial hardship from medical bills. Patients unable to pay medical bills had 1.9-times higher odds of emergency department visits (aOR, 1.85 [1.33-2.57]) and 1.8-times higher odds of missing work due to disease (aOR, 1.83 [1.26-2.67]).

Conclusions

One in 3 adults with CLD experience financial hardship from medical bills, and frequently experience financial toxicity and unplanned healthcare use. These financial determinates of health have important implications in the context of value-based care.

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