Editorial
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Stress proteins: Is their application in clinical medicine on the horizon?
Ivor J. Benjamin M. D.,
Corresponding Author
Ivor J. Benjamin M. D.
Department of Internal Medicine Molecular Cardiology Research Laboratories University of Texas Southwestern Medical Center Dallas, Texas 75235
Department of Internal Medicine, Molecular Cardiology, Research Laboratories, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75235===Search for more papers by this authorIvor J. Benjamin M. D.,
Corresponding Author
Ivor J. Benjamin M. D.
Department of Internal Medicine Molecular Cardiology Research Laboratories University of Texas Southwestern Medical Center Dallas, Texas 75235
Department of Internal Medicine, Molecular Cardiology, Research Laboratories, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75235===Search for more papers by this author
References
- 1 Lindquist S, Craig EA. The heat-shock proteins. Annu Rev Genet 1988; 22: 631–677.
- 2 Morimoto RI, Milarski KL. Expression of vertebrate hsp 70 genes. In: R Morimoto, A Tissieres, C Georgopoulos, eds. Stress proteins in biology and medicine. Cold Springs Harbor, NY: Cold Spring Harbor Press, 1989: 323–359.
- 3 Jorge AD, Stati AO, Roig LV, Ponce G, Jorge OA, Ciocca RD. Steroid receptors and heat shock proteins in patients with primary biliary cirrhosis. Hepatology 1993; 18: 1108–1114.
- 4 Gething MJ, Sambrook S. Protein folding in the cell. Nature 1992; 355: 33–55.
- 5 Welch WJ. The mammalian stress response: cell physiology and biochemistry of stress proteins. In R Morimoto, A Tissieres, C Georgopoulos, eds. Stress proteins in biology and medicine. Cold Spring Harbor, NY: Cold Spring Harbor Press, 1989: 223–278.
- 6 Burroughs AK, Butler P, Sternberg MJ, Baum H. Molecular mimicry in liver disease. Nature 1992; 358: 377–378.
- 7 Winfield JB. Stress proteins, arthritis, and autoimmunity. Arthr Rheum 1989; 32: 1497–1504.
- 8 Wing SS, Chiang H-L, Goldberg AL, Dice JF. Proteins containing peptide sequences related to Lys-Phe-Glu-Arg-Gin are selectively depleted in the livers and hearts, but not skeletal muscle, of fasted rats. Biochem J 1991; 275: 165–169.
- 9 Heydari AR, Wu B, Takahashi R, Strong R, Richardson A. Expression of the heat shock protein 70 is altered by age and diet at the level of transcription. Mol Cell Biol 1993; 13: 2909–2918.
- 10 Williams RS, Thomas JA, Fina M, German Z, Benjamin IJ. Human Hsp70 protects human cells from injury during metabolic stress. J Clin Invest 1993; 92: 503–508.
- 11 Brown IR, Rush SJ. Expression of the heat shock protein (hsp70) in the mammalian brain: distinguishing constitutively expressed and hyperthermia-inducible mRNA. J Neuro Res 1993; 25: 14–19.
- 12 Udelsman M, Blake R, Stagg CA, Li DG, Putney DJ, Holbrook NJ. Vascular heat shock protein expression in response to stress. J Clin Invest 1993; 91: 465–473.
