Hepatocyte enlargement and portal hypertension
Hector Orrego M.D., F.R.C.P. (C)
Addiction Research Foundation and, Departments of Medicine and Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 2S1
Search for more papers by this authorLaurence M. Blendis M.D., F.R.C.P. (C)
Addiction Research Foundation and, Departments of Medicine and Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 2S1
Search for more papers by this authorYedy Israel Ph.D.
Addiction Research Foundation and, Departments of Medicine and Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 2S1
Search for more papers by this authorHector Orrego M.D., F.R.C.P. (C)
Addiction Research Foundation and, Departments of Medicine and Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 2S1
Search for more papers by this authorLaurence M. Blendis M.D., F.R.C.P. (C)
Addiction Research Foundation and, Departments of Medicine and Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 2S1
Search for more papers by this authorYedy Israel Ph.D.
Addiction Research Foundation and, Departments of Medicine and Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 2S1
Search for more papers by this author
References
- 1 Mastai R, Huet MP, Brault A, Belgiorno J. The rat liver microcirculation in alcohol-induced hepatomegaly. Hepatology 1989; 10: 941–945.
- 2 Orrego H, Blendis LM, Crossley IR, Medline A, Macdonald A, Ritchie S, Israel Y. Correlation of intrahepatic pressure with collagen in the Disse space and hepatomegaly in humans and in the rat. Gastroenterology 1981; 80: 546–556.
- 3 Blendis M, Orrego H, Crossley IR, Blake JE, Medline A, Israel Y. The role of hepatocyte enlargement in hepatic pressure in cirrhotic and noncirrhotic alcoholic liver disease. Hepatology 1982; 2: 539–546.
- 4 Israel Y, Britton RS, Orrego H. Liver cell enlargement induced by chronic alcohol consumption: studies on its causes and consequences. Clin Biochem 1982; 15: 189–192.
- 5 Vidins EI, Britton RS, Medline A, Blendis LM, Israel Y, Orrego H. Sinusoidal caliber in alcoholic and nonalcoholic liver disease: diagnostic and pathogenic implications. Hepatology 1985; 5: 408–414.
- 6 Bredfeldt JE, Riley EM, Groszmann RJ. Intrahepatic pressure and portal pressure in alcoholic rats [Abstract]. Hepatology 1981; 1: 399.
- 7 Finucci GF, Merkel C, Terribile Wiel Marin V, Fecchio MT, Bellon S, Gatta A, Zuin R. Hepatocyte enlargement contributes to portal hypertension in chronic liver disease [Abstract]. J Hepatol 1987; 5: 5126.
- 8 Lee SS, Hadangue A, Girod C, Braillon A, Lebrec D. Reduction of intrahepatic vascular space in the pathogenesis of portal hypertension. In vitro and in vivo studies in the rat. Gastroenterology 1987; 93: 157–161.
- 9 Shibayama Y. On the pathogenesis of portal hypertension in cirrhosis of the liver. Liver 1988; 8: 95–99.
- 10 Shibayama Y, Nakata K. The role of sinusoidal stenosis in portal hypertension of liver cirrhosis. J Hepatol 1989; 8: 60–66.
- 11 Sato H, Takase S, Takada A. Changes in liver and spleen volumes in alcoholic liver disease. J Hepatol 1989; 8: 150–157.
- 12 Tarao K, Hoshino H, Motohashi I, Iimori K, Tamai S, Ito Y, Takagi S, et al. Changes in liver and spleen volume in alcoholic liver fibrosis of man. Hepatology 1989; 9: 589–593.
- 13 Valla D, Flejou JF, Lebrec D, Bernuau J, Rueff B, Salzmann JL, Benhamou JP. Portal hypertension and ascites in acute hepatitis: clinical, hemodynamic and histological correlations. Hepatology 1989; 10: 482–487.
- 14 Israel Y, Kalant H, Orrego H, Khanna JM, Videla L, Phillips JM. Experimental alcohol-induced hepatic necrosis: suppression by propylthiouracil. Proc Natl Acad Sci 1975; 72: 1137–1141.
