ORIGINAL ARTICLE

Rational choice of neck dissection in clinically N0 patients with supraglottic cancer

Ye Zhang MD

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China

Ye Zhang and Siyuan Xu contributed equally to this work.Search for more papers by this author

Siyuan Xu MD,

Siyuan Xu MD

Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China

Ye Zhang and Siyuan Xu contributed equally to this work.Search for more papers by this author

Wensheng Liu MD,

Wensheng Liu MD

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Xiaolei Wang MD,

Xiaolei Wang MD

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Kai Wang MD,

Kai Wang MD

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Shaoyan Liu MD,

Shaoyan Liu MD

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Zhengang Xu MD,

Corresponding Author

Zhengang Xu MD

[email protected]

Correspondence

Jie Liu and Zhengang Xu, Department of Head and Neck Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing 10021, PR China.

Email: [email protected] (J. L.), [email protected] (Z. X.)

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Jie Liu MD,

Corresponding Author

Jie Liu MD

[email protected]

orcid.org/0000-0003-3975-7978

Correspondence

Email: [email protected] (J. L.), [email protected] (Z. X.)

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Ye Zhang MD,

Ye Zhang MD

Ye Zhang and Siyuan Xu contributed equally to this work.Search for more papers by this author

Siyuan Xu MD,

Siyuan Xu MD

Ye Zhang and Siyuan Xu contributed equally to this work.Search for more papers by this author

Wensheng Liu MD,

Wensheng Liu MD

Search for more papers by this author

Xiaolei Wang MD,

Xiaolei Wang MD

Search for more papers by this author

Kai Wang MD,

Kai Wang MD

Search for more papers by this author

Shaoyan Liu MD,

Shaoyan Liu MD

Search for more papers by this author

Zhengang Xu MD,

Corresponding Author

Zhengang Xu MD

[email protected]

Correspondence

Email: [email protected] (J. L.), [email protected] (Z. X.)

Search for more papers by this author

Jie Liu MD,

Corresponding Author

Jie Liu MD

[email protected]

orcid.org/0000-0003-3975-7978

Correspondence

Email: [email protected] (J. L.), [email protected] (Z. X.)

Search for more papers by this author

First published: 14 November 2019

https://doi.org/10.1002/hed.26014

Citations: 16

Section Editor: William Mendenhall

Funding information: CAMS Innovation Fund for Medical Sciences (CIFMS), Grant/Award Number: Grant no.2016-I2M-1-001

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Abstract

Background

The mainstay treatment of the neck for clinically negative neck (cN0) supraglottic laryngeal carcinoma (SGLC) is neck dissection. However, the optimal extent remains controversial. This study's purpose is to determine whether ipsilateral level II-III neck dissection is appropriate for cN0SGLC patients.

Methods

The records of 220 consecutive untreated cN0SGLC patients were retrospectively reviewed. Relevant factors related to occult and contralateral neck metastasis were analyzed and the distribution of metastasis was described.

Results

Seventy-seven and 143 patients underwent unilateral and bilateral neck dissection, respectively. The rate of occult neck metastases was 21.4%. The histologic differentiation was an independent risk factor for occult neck metastasis. In the bilateral neck dissection group, the incidence of contralateral neck metastasis of patients with noncentral tumors was 0.7%. Moreover, only 1.7% of patients had positive nodes at level IV, and no isolated nodal metastases existed in level IV.

Conclusion

Ipsilateral level II-III neck dissection is feasible for patients with noncentral cN0SGLC.

CONFLICT OF INTEREST

The authors have no conflicts of interest to disclosure.

REFERENCES

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Volume42, Issue3

March 2020

Pages 365-373

Rational choice of neck dissection in clinically N0 patients with supraglottic cancer

Abstract

Background

Methods

Results

Conclusion

CONFLICT OF INTEREST

REFERENCES

Citing Literature

References

Information

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Rational choice of neck dissection in clinically N0 patients with supraglottic cancer

Abstract

Background

Methods

Results

Conclusion

CONFLICT OF INTEREST

REFERENCES

Citing Literature

References

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