Volume 41, Issue 1 pp. 72-78
ORIGINAL ARTICLE

Sclerosis of the arytenoid cartilage and glottic carcinoma: A clinical-pathological study

Marco Lucioni MD

Marco Lucioni MD

Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy

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Marco Lionello MD

Corresponding Author

Marco Lionello MD

Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy

Correspondence

Marco Lionello, MD, Otolaryngology Unit, Vittorio Veneto Hospital, Vittorio Veneto, via Forlanini 71, 31029, Treviso, Italy.

Email: [email protected]

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Piernicola Machin MD

Piernicola Machin MD

Pathology Section, Conegliano Hospital, Treviso, Italy

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Federica Sovran MD

Federica Sovran MD

Radiology Unit, Vittorio Veneto Hospital, Treviso, Italy

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Fabio Canal MD

Fabio Canal MD

Pathology Section, Conegliano Hospital, Treviso, Italy

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Andy Bertolin MD

Andy Bertolin MD

Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy

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Giuseppe Rizzotto MD

Giuseppe Rizzotto MD

Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy

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First published: 07 December 2018
Citations: 9
All procedures performed in the study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee, and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Abstract

Background

Given the relevance of any tumor invasion of the arytenoid cartilage or crico-arytenoid unit to the planning open partial horizontal laryngectomy (OPHL) for laryngeal squamous cell carcinoma (LSCC), it is important to have a reliable radiological test to assess impairments of these structures.

Methods

We retrospectively compared the endoscopic, radiological, and pathological findings in patients with glottic LSCC who underwent OPHL.

Results

The endoscopic finding of a reduced (impaired or absent) vocal cord motility proved more sensitive, with better positive and negative predictive values, but less specific than the radiological finding of complete arytenoid sclerosis in detecting histologically assessable infiltration of the arytenoid cartilage.

Conclusions

Endoscopy retains a key role in the preoperative workup for glottic LSCC. CT evidence of complete sclerosis of the arytenoid cartilage is related to a dangerous contiguity of the tumor to the cartilage.

CONFLICT OF INTEREST

Conflict of interest declared: none.

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