Novel method to save the parathyroid gland during thyroidectomy: Subcapsular saline injection
Corresponding Author
June Young Choi MD
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
June Young Choi and Hyeong Won Yu contributed equally to this article as co-first authors.
Correspondence June Young Choi, Endocrine Surgery/Department of Surgery, Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do #13620, Korea. Email: [email protected]Search for more papers by this authorHyeong Won Yu MD
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea
June Young Choi and Hyeong Won Yu contributed equally to this article as co-first authors.
Search for more papers by this authorIn Eui Bae MD
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea
Search for more papers by this authorJong-kyu Kim MD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Search for more papers by this authorChan Yong Seong MD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Search for more papers by this authorJin Wook Yi MD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Search for more papers by this authorYoung Jun Chai MD
Department of Surgery, Seoul National University Boramae Medical Center, Dongjak-gu, Seoul, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Search for more papers by this authorSu-jin Kim MD, PhD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Search for more papers by this authorKyu Eun Lee MD, PhD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Search for more papers by this authorCorresponding Author
June Young Choi MD
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
June Young Choi and Hyeong Won Yu contributed equally to this article as co-first authors.
Correspondence June Young Choi, Endocrine Surgery/Department of Surgery, Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do #13620, Korea. Email: [email protected]Search for more papers by this authorHyeong Won Yu MD
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea
June Young Choi and Hyeong Won Yu contributed equally to this article as co-first authors.
Search for more papers by this authorIn Eui Bae MD
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea
Search for more papers by this authorJong-kyu Kim MD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Search for more papers by this authorChan Yong Seong MD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Search for more papers by this authorJin Wook Yi MD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Search for more papers by this authorYoung Jun Chai MD
Department of Surgery, Seoul National University Boramae Medical Center, Dongjak-gu, Seoul, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Search for more papers by this authorSu-jin Kim MD, PhD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Search for more papers by this authorKyu Eun Lee MD, PhD
Department of Surgery, Seoul National University Hospital and College of Medicine, Jongno-gu, Seoul, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Search for more papers by this authorAbstract
Background
Saving the parathyroid gland during thyroidectomy remains challenging. Subcapsular saline injection (SCASI) was developed in February 2015. Its ability to spare the parathyroid gland was assessed.
Methods
All consecutive patients who underwent total thyroidectomy with or without neck lymph node dissection in 2013-2015 were included in this retrospective cohort study. Patients were divided into the SCASI and non-SCASI groups. Serum parathyroid hormone (PTH) levels were measured on day 1 and 6 months after surgery. Transient and permanent hypoparathyroidism were defined as day 1 and 6 month PTH < 10.0 and <15.0 pg/mL, respectively.
Results
The groups (both had 98 patients each) did not differ in demographics, tumor size, operation extent, pathology, thyroiditis rate, and incidental parathyroid gland excision rate. Compared with non-SCASI patients, patients who underwent the SCASI method exhibited transient hypoparathyroidism (35.7% vs 19.4%, P < .001) and permanent hypoparathyroidism (4.1% vs 0%, P = .043) significantly less frequently.
Conclusion
The procedure of SCASI effectively spared the parathyroid gland during thyroidectomy.
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