One-year quality of life and functional outcomes of transoral robotic surgery for carcinoma of unknown primary
Isa Ozbay MD
Department of Otolaryngology, Dumlupinar University, Kutahya, Turkey
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Search for more papers by this authorAli Cemal Yumusakhuylu MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Department of Otolaryngology, Marmara University, Istanbul, Turkey
Search for more papers by this authorRishabh Sethia BS
College of Medicine, The Ohio State University, Columbus, Ohio
Search for more papers by this authorLai Wei PhD
Department of Biomedical, The Ohio State University, Columbus, Ohio
Search for more papers by this authorMatthew Old MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Search for more papers by this authorAmit Agrawal MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Search for more papers by this authorTheodoros Teknos MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Search for more papers by this authorCorresponding Author
Enver Ozer MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Correspondence Enver Ozer, Department of Otolaryngology - Head and Neck Surgery, Wexner Medical Center at The Ohio State University, 320 W 10th Avenue, Starling Loving Hall, Room B216, Columbus, OH 43210., Email: [email protected]Search for more papers by this authorIsa Ozbay MD
Department of Otolaryngology, Dumlupinar University, Kutahya, Turkey
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Search for more papers by this authorAli Cemal Yumusakhuylu MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Department of Otolaryngology, Marmara University, Istanbul, Turkey
Search for more papers by this authorRishabh Sethia BS
College of Medicine, The Ohio State University, Columbus, Ohio
Search for more papers by this authorLai Wei PhD
Department of Biomedical, The Ohio State University, Columbus, Ohio
Search for more papers by this authorMatthew Old MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Search for more papers by this authorAmit Agrawal MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Search for more papers by this authorTheodoros Teknos MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Search for more papers by this authorCorresponding Author
Enver Ozer MD
Department of Otolaryngology - Head and Neck Surgery, “Arthur G. James” Cancer Hospital and “Richard J. Solove” Research Institute, Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio
Correspondence Enver Ozer, Department of Otolaryngology - Head and Neck Surgery, Wexner Medical Center at The Ohio State University, 320 W 10th Avenue, Starling Loving Hall, Room B216, Columbus, OH 43210., Email: [email protected]Search for more papers by this authorAbstract
Background
The purpose of this study was to assess the quality of life (QOL) outcomes in patients who underwent transoral robotic surgery (TORS) for carcinoma of unknown primary (CUP).
Methods
Twenty-nine patients with CUP were administered the Head and Neck Cancer Inventory (HNCI) prospectively to evaluate QOL preoperatively and postoperatively.
Results
There was statistically and clinically significant deterioration in 2 of 4 domains (eating and social disruption) in the immediate aftermath of TORS. There was statistically and clinically meaningful deterioration in all 4 domains at 3 months relative to baseline, and there remained statistically and clinically meaningful deterioration in 2 of 4 domains at 6 months compared to baseline. These 2 domains remained statistically and clinically worse than baseline at 12 months. Speech and aesthetics domain scores were comparable at baseline and 12 months.
Conclusion
Patients reported difficulties with eating and social disruption over the course of 1 year, but problems with speech and appearance abated.
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