Research Article
Free to Read
Synthesis of novel oxazolines and application in cyanosilylation of prochiral ketones
Abstract
A new family of oxazolines was synthesized in high yields and was characterized by NMR, IR, and MS. Oxazoline–lanthanide complexes, as the novel Lewis acid catalysts, were applied to the asymmetric cyanosilylation of ketones that gave the corresponding cyanohydrin trimethylsilyl ethers in moderate yields and enantioselectivities under mild conditions. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:679–683, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20374
