The first general synthesis of 3-iodo-4-R-furazans
Corresponding Author
Aleksei B. Sheremetev
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47, Leninsky Prosp., Moscow 119991, Russia
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47, Leninsky Prosp., Moscow 119991, RussiaSearch for more papers by this authorJulia L. Shamshina
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47, Leninsky Prosp., Moscow 119991, Russia
Search for more papers by this authorDmitry E. Dmitriev
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47, Leninsky Prosp., Moscow 119991, Russia
Search for more papers by this authorDenis V. Lyubetskii
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Street B-334, Moscow 119991, Russia
Search for more papers by this authorMikhail Yu. Antipin
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Street B-334, Moscow 119991, Russia
Search for more papers by this authorCorresponding Author
Aleksei B. Sheremetev
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47, Leninsky Prosp., Moscow 119991, Russia
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47, Leninsky Prosp., Moscow 119991, RussiaSearch for more papers by this authorJulia L. Shamshina
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47, Leninsky Prosp., Moscow 119991, Russia
Search for more papers by this authorDmitry E. Dmitriev
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47, Leninsky Prosp., Moscow 119991, Russia
Search for more papers by this authorDenis V. Lyubetskii
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Street B-334, Moscow 119991, Russia
Search for more papers by this authorMikhail Yu. Antipin
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Street B-334, Moscow 119991, Russia
Search for more papers by this authorAbstract
The first general synthetic route has been developed for the convenient preparation of iodofurazans. The approach was accomplished by one-pot diazotization-iodation reaction of appropriate aminofurazans. A combination of sodium nitrite and iodine in organic solvent under anhydrous conditions as the reaction conditions allowed to solve problem in iodofurazans preparation. The investigation of the substituent's influence on NMR data of the iodofurazans has been carried out. The X-ray crystal structure of the 3-amino-4-iodofurazan 1d is reported. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:199–207, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20007
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