Four relative-pair methods for detecting genetic linkage were applied to familial Alzheimer's disease data. Results obtained using an extended Haseman-Elston test and a weighted rank pairwise correlation test, which both use information from all relative pairs, were consistent with previously published likelihood results and appear to be more powerful than affected sib pair methods. © 1993 Wiley-Liss, Inc.

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Volume10, Issue6

1993

Pages 377-382

Linkage analysis of Alzheimer's disease with methods using relative pairs

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Linkage analysis of Alzheimer's disease with methods using relative pairs

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