A conditional floxed (loxP-flanked) allele for the retinoic acid receptor beta (RARβ) gene
Benoit Chapellier
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorManuel Mark
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorJulie Bastien
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorAndrée Dierich
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorMarianne LeMeur
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorCorresponding Author
Pierre Chambon
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, BP 163, 67404 Illkirch Cedex, CU de Strasbourg, FranceSearch for more papers by this authorNorbert B. Ghyselinck
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorBenoit Chapellier
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorManuel Mark
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorJulie Bastien
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorAndrée Dierich
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorMarianne LeMeur
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this authorCorresponding Author
Pierre Chambon
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, BP 163, 67404 Illkirch Cedex, CU de Strasbourg, FranceSearch for more papers by this authorNorbert B. Ghyselinck
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Collège de France, Strasbourg, France
Search for more papers by this author
LITERATURE CITED
- Chambon P. 1996. A decade of molecular biology of retinoic acid receptors. FASEB J 10: 940–954.
- Dupé V, Davenne M, Brocard J, Dollé P, Mark M, Dierich A, Chambon P, Rijli FM. 1997. In vivo functional analysis of the Hoxa-1 3′ retinoic acid response element (3′RARE). Development 124: 339–410.
- Ghyselinck NB, Dupé V, Dierich A, Messaddeq N, Garnier JM, Rochette-Egly C, Chambon P, Mark M. 1997. Role of the retinoic acid receptor beta (RARbeta) during mouse development. Int J Dev Biol 41: 425–447.
- Kastner P, Mark M, Chambon P. 1995. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life. Cell 83: 859–869.
- Kastner P, Mark M, Ghyselinck N, Krezel W, Dupé V, Grondona JM, Chambon P. 1997. Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development. Development 124: 313–326.
- Mark M, Ghyselinck NB, Wendling O, Dupé V, Mascrez B, Kastner P, Chambon P. 1999. A genetic dissection of the retinoid signalling pathway in the mouse. Proc Nutr Soc 58: 609–613.
- Mascrez B, Mark M, Dierich A, Ghyselinck NB, Kastner P, Chambon P. 1998. The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development. Development 125: 4691–4707.
- Mattei MG, Riviere M, Krust A, Ingvarsson S, Vennstrom B, Islam MQ, Levan G, Kastner P, Zelent A, Chambon P, Szpirer J, Szpirer C. 1991. Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes. Genomics 10: 1061–1069.
- Metzger D, Chambon P. 2001. Site- and time-specific gene targeting in the mouse. Methods 24: 71–80.
- Metzger D, Clifford J, Chiba H, Chambon P. 1995. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci USA 92: 6991–6995.
- Rochette-Egly C, Gaub MP, Lutz Y, Ali S, Scheuer I, Chambon P. 1992. Retinoic acid receptor beta: Immunodetection and phosphorylation on tyrosine residues. Mol Endocrinol 6: 2197–2209.
- Zelent A, Krust A, Petkovich M, Kastner P, Chambon P. 1989. Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin. Nature 339: 714–717.
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