Seizure-associated takotsubo cardiomyopathy with Alzheimer's disease: A case report
Takehito Kuroda
Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorCorresponding Author
Tomotaka Tanaka
Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan
Correspondence
Tomotaka Tanaka, Department of Neurology, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka 564-8565, Japan.
Email: [email protected]
Search for more papers by this authorSoichiro Abe
Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorManabu Inoue
Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorYoshiaki Morita
Department of Radiology, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorTakuto Mukaida
Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorTakamasa Iwai
Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorMasafumi Ihara
Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorTakehito Kuroda
Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorCorresponding Author
Tomotaka Tanaka
Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan
Correspondence
Tomotaka Tanaka, Department of Neurology, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka 564-8565, Japan.
Email: [email protected]
Search for more papers by this authorSoichiro Abe
Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorManabu Inoue
Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorYoshiaki Morita
Department of Radiology, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorTakuto Mukaida
Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorTakamasa Iwai
Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this authorMasafumi Ihara
Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan
Search for more papers by this author
CONFLICT OF INTEREST STATEMENT
The authors have no competing interests to declare relevant to this article's content.
Open Research
DATA AVAILABILITY STATEMENT
All data generated or analyzed during this study are included in this published article.
Supporting Information
Filename | Description |
---|---|
epd220128-sup-0001-Test_Yourself_Answers.docxWord 2007 document , 13.3 KB |
Test Yourself Answers |
epd220128-sup-0002-FigureS1.docxWord 2007 document , 1,007.7 KB |
Figure S1. |
epd220128-sup-0003-Educational_slides.pptxapplication/application/vnd.openxmlformats-officedocument.presentationml.presentation, 15 MB |
Educational Slides |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
REFERENCES
- 1Stöllberger C, Wegner C, Finsterer J. Seizure-associated takotsubo cardiomyopathy. Epilepsia. 2011; 52(11): e160–e167.
- 2Vossel KA, Ranasinghe KG, Beagle AJ, Mizuiri D, Honma SM, Dowling AF, et al. Incidence and impact of subclinical epileptiform activity in Alzheimer's disease. Ann Neurol. 2016; 80(6): 858–870.
- 3Lam AD, Sarkis RA, Pellerin KR, Jing J, Dworetzky BA, Hoch DB, et al. Association of epileptiform abnormalities and seizures in Alzheimer disease. Neurology. 2020; 95(16): e2259–e2270.
- 4Chatzikonstantinou A, Gass A, Förster A, Hennerici MG, Szabo K. Features of acute DWI abnormalities related to status epilepticus. Epilepsy Res. 2011; 97(1–2): 45–51.
- 5Cole AJ. Status epilepticus and periictal imaging. Epilepsia. 2004; 45(Suppl 4): 72–77.
- 6Desai R, Singh S, Patel U, Fong HK, Kaur VP, Varma Y, et al. Frequency of takotsubo cardiomyopathy in epilepsy-related hospitalizations among adults and its impact on in-hospital outcomes: a national standpoint. Int J Cardiol. 2020; 299: 67–70.
- 7Oppenheimer SM, Gelb A, Girvin JP, Hachinski VC. Cardiovascular effects of human insular cortex stimulation. Neurology. 1992; 42(9): 1727–1732.
- 8Santoro F, Carapelle E, Cieza Ortiz SI, Musaico F, Ferraretti A, d'Orsi G, et al. Potential links between neurological disease and Tako-Tsubo cardiomyopathy: a literature review. Int J Cardiol. 2013; 168(2): 688–691.
- 9Zhang D, Chen S, Xu S, Wu J, Zhuang Y, Cao W, et al. The clinical correlation between Alzheimer's disease and epilepsy. Front Neurol. 2022; 13:922535.
- 10Vossel K, Ranasinghe KG, Beagle AJ, La A, Ah Pook K, Castro M, et al. Effect of levetiracetam on cognition in patients with Alzheimer disease with and without epileptiform activity: a randomized clinical trial. JAMA Neurol. 2021; 78(11): 1345–1354.
- 11Cerri AP, Teruzzi F, Gregorio M, Bellelli G, Annoni G. Takotsubo cardiomyopathy in an elderly patient with severe Alzheimer's disease: a case report. J Am Med Dir Assoc. 2012; 13(3): 207–209.
- 12Guidoni SV, Pellicano C, La Starza S, Spalloni A, Rasura M. Tako tsubo and ischemic stroke in a patient with Alzheimer's disease. Aging Clin Exp Res. 2014; 26(6): 673–675.
- 13Zuin M, Dal Santo P, Picariello C, Conte L, Zuliani G, D'Elia K, et al. Takotsubo cardiomyopathy in an elderly woman with Alzheimer's disease: a rare association. Case report and mini-review of the literature. J Am Geriatr Soc. 2016; 64(4): 916–917.
- 14Moulin Mares SRA, Groner JS, de Oliveira MP, Lírio LV, Coutinho PC, Luchi WM. Takotsubo cardiomyopathy in an Alzheimer disease patient: the potential contribution of antidepressant agents. Alzheimer Dis Assoc Disord. 2020; 34(4): 360–361.
- 15Segers K, Mihailescu T, Kazadi A, Benoit F, Surquin M. Takotsubo cardiomyopathy as a consequence of acute anxiety in a patient with Alzheimer's disease associated with Lewy body disease. Psychogeriatrics. 2020; 20(4): 528–529.
- 16Ito M, Fukui K, Miyamoto N, Kato H, Miki K, Shiobara K, et al. Takotsubo cardiomyopathy in a bedridden patient with dementia and communication difficulties due to Alzheimer's disease. J Rural Med. 2022; 17(2): 89–93.
- 17Pike CJ. Sex and the development of Alzheimer's disease. J Neurosci Res. 2017; 95(1–2): 671–680.
- 18Kuo BT, Choubey R, Novaro GM. Reduced estrogen in menopause may predispose women to takotsubo cardiomyopathy. Gend Med. 2010; 7(1): 71–77.