The germ-line V gene segments encoding the subgroups A and G of the BALB/c V_χ21 family were cloned and assigned to the previously described 30-kb cluster of the V_χ21 family. Sequence comparison revealed close homology between the two gene segments at the DNA and the predicted amino acid sequence level, indicating that V_χ21A and V_χ21G originated by a rather recent gene duplication.

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Volume19, Issue10

October 1989

Pages 1961-1963

Sequence and linkage of the v_χ21a and g germ-line gene segments in the mouse

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Sequence and linkage of the vχ21a and g germ-line gene segments in the mouse

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Sequence and linkage of the v_χ21a and g germ-line gene segments in the mouse