Volume 16, Issue 5 pp. 422-428
Clinical Investigation
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A simultaneous study of doppler-echo and catheterization in noninvasive assessment of the left ventricular dp/dt

Zhiming Ge M.D.

Corresponding Author

Zhiming Ge M.D.

Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Department of Cardiovascular Diseases (MBC 16) King Faisal Specialist Hospital PO Box 3354 Riyadh 11211, Saudi ArabiaSearch for more papers by this author
Carlos Duran M.D., PH.D.

Carlos Duran M.D., PH.D.

Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Yun Zhang M.D., PH.D.

Yun Zhang M.D., PH.D.

Department of Cardiology, Shandong Medical University Hospital, Jinan, Peoples' Republic of China

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Weigiang Kang M.D.

Weigiang Kang M.D.

Department of Cardiology, Shandong Medical University Hospital, Jinan, Peoples' Republic of China

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Dongsheng Fan M.D.

Dongsheng Fan M.D.

Department of Cardiology, Shandong Medical University Hospital, Jinan, Peoples' Republic of China

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First published: May 1993
Citations: 9

Abstract

To confirm the feasibility and accuracy of the method for the noninvasive measurement of the left ventricular dp/dt, 53 patients with mitral regurgitation underwent simultaneous determination of left ventricular dp/dt by continuous-wave Doppler echocardiography and cardiac catheterization. Doppler-determined left ventricular dp/dt is derived from the Doppler mitral regurgitant spectrum by dividing the magnitude of the left ventricular-atrial pressure gradient rise between 1 and 3 m/s of the mitral regurgitant velocity signal by the time taken for this change. Left ventricular dp/dt by Doppler ranged from 629 to 3494 mmHg/s (x̄ ± SD, 1971 ± 785 mmHg/s), and that by catheterization varied between 716 and 3650 mmHg/s (x̄ ± SD, 1974 ± 727 mmHg/s). There was a high correlation (r = 0.93, y = 0.862 × + 274.77, SEE = 271 mmHg/s, p < 0.001) of left ventricular dp/dt between the two techniques. It is concluded that left ventricular dp/dt is one of the most commonly used parameters for the evaluation of left ventricular systolic function and that Doppler echocardiography provides a new, accurate and noninvasive method of evaluation.

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