Characterization, Crystal Structure and Initial DNA Binding Interaction of Two Cu(II) Complexes with 4,5-Diazafluoren-9-one
Yan-Hong SONG
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorRong-Lan ZHANG
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorQing-Jin SUN
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorZhan-Wei XU
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorQuan-Chang GAO
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorHua-Qiang LIU
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorYan-Hong SONG
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorRong-Lan ZHANG
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorQing-Jin SUN
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorZhan-Wei XU
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorQuan-Chang GAO
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorHua-Qiang LIU
Shaanxi Key Laboratory of Physico-inorganic Chemistry, Department of Chemistry, Northwest University, Xi'an, Shaanxi 710069, China
Search for more papers by this authorAbstract
Two new complexes [Cu(dafo)2(en)](ClO4)2·2H2O (en=NH2CH2CH2NH2) 1 and [Cu(dafo)2(dap)](ClO4)2· 2H2O [dap=NH2CH2CH(CH3)NH2] 2 (dafo=4,5-diazafluoren-9-one) have been synthesized and characterized by elemental analysis, IR and UV spectra. Meanwhile, the complex 1 has been characterized by single crystal X-ray diffraction analysis. The initial DNA binding interactions of the complexes 1 and 2 have been investigated by UV spectra, emission spectra and cyclic voltammogram. Concluding the results of three methods used to measure the interaction of complexes 1 and 2 with DNA, the action mode of the two complexes with DNA is intercalation, and character of ligands and steric effect may affect the interaction of the complexes with DNA.
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