Liquid-Phase Synthesis of Methyl (2Z)-2-Arylsulfonylmethyl-2- alkenoates from PEG-Supported α-Phenylselenopropionate
Qiong Wang
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorShu-Ying Lin
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorLei Guo
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorMei-Hong Wei
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorXian Huang
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorQiong Wang
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorShu-Ying Lin
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorLei Guo
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorMei-Hong Wei
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorXian Huang
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
Search for more papers by this authorAbstract
Treatment of lithio derivative of novel PEG-supported (-phenylselenopropionate with aldehydes, followed by oxidation-elimination with 30% hydrogen peroxide, formed Baylis-Hillman products, which were then reacted with sodium arylsulfinate. The resulting sulfonylated products were cleaved from the PEG efficiently affording methyl (2Z)-2-arylsulfonylmethyl-2-alkenoates in good yields and high purities.
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