Triphenylphosphine-Catalyzed Michael Addition of Alcohols to Acrylic Compounds
Hai-Ling Liu
Centre of Green Chemistry, College of Chemistry, South China University of Technology, Guangzhou, Guangdong 510640, China
Search for more papers by this authorHuan-Feng Jiang
Tel.: 0086-020-22236518; Fax: 0086-020-87112906
Search for more papers by this authorYu-Gang Wang
Centre of Green Chemistry, College of Chemistry, South China University of Technology, Guangzhou, Guangdong 510640, China
Search for more papers by this authorHai-Ling Liu
Centre of Green Chemistry, College of Chemistry, South China University of Technology, Guangzhou, Guangdong 510640, China
Search for more papers by this authorHuan-Feng Jiang
Tel.: 0086-020-22236518; Fax: 0086-020-87112906
Search for more papers by this authorYu-Gang Wang
Centre of Green Chemistry, College of Chemistry, South China University of Technology, Guangzhou, Guangdong 510640, China
Search for more papers by this authorAbstract
A facile triphenylphosphine-catalyzed Michael addition of alcohols to acrylic compounds was described. The reaction was carried out in open air at refluxing temperature in the presence of 10 mol% PPh3. Michael addition of saturated and unsaturated alcohols to acrylonitrile or acrylates has been examined. The reaction gave β-alkoxy derivatives with isolated yields of 5%–79%. PPh3 is cheaper and more stable than those trialkylphosphines previously used for the similar reactions, and the products can be easily separated from the reaction mixture via distillation.
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