Synthesis of Novel Nucleoside Analogues Based on 1,3-Dihydrobenzo[c]furan Core
Abstract
A novel efficient synthetic route to 1,3-dihydrobenzo[c]furan glycone was developed and the corresponding 5-fluoro, 5-iodo uracil and guanosine derivatives, the aromatic analogues of the well known antiviral 2′,3′-dideoxy-2′,3′-dihydronucleosides (d4N), were synthesized.