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Synthesis and Antibacterial Activity of 3-(5-Methylisoxazol-3-yl) −1,2,4-triazolo [3,4-b]-1,3,4-thiadiazine Derivatives
Abstract
The condensed products 2-10 of 4-amino-5-mercapto-3-(5-methylisoxazol-3-yl)-l,2,4-triazole (1) with chloroacetaldehyde, 2-bromocyclohexanone, chloranil, ωbromo-ω-(1H-1, 2,4-triazol-l-yl)acetophenone, 2-bromo-4′-substituted acetophenones and 2-bromo-6′-methoxy-2′-acetonaphthone were described. The antibacterial activities were also evaluated.
