Highly Enantioselective Microbial Hydrolysis of cis-2-Arylcyclopropanecarbonitriles^†

Guo-Qiang Feng,

Guo-Qiang Feng

Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China

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Mei-Xiang Wang,

Mei-Xiang Wang

[email protected]

Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China

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Guo-Qiang Feng,

Guo-Qiang Feng

Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China

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Mei-Xiang Wang,

Mei-Xiang Wang

[email protected]

Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China

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First published: 26 August 2010

https://doi.org/10.1002/cjoc.20010190120

Citations: 10

^†

Special paper from the “China-Netherlands Bilateral Symposium on Organometallic Chemistry and Catalysis”, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China, 1999.

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Abstract

Hydrolysis of racemic cis-2-arylcyclopropanecarbonitriles catalyzed by Rhodococcus sp. AJ270 whole cells proceeded enantioselectively to afford the corresponding amide and acid with enantiomeric excess higher than 99%.

References

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Volume19, Issue1

January 2001

Pages 113-115

Highly Enantioselective Microbial Hydrolysis of cis-2-Arylcyclopropanecarbonitriles^†

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Highly Enantioselective Microbial Hydrolysis of cis-2-Arylcyclopropanecarbonitriles†

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Highly Enantioselective Microbial Hydrolysis of cis-2-Arylcyclopropanecarbonitriles^†