Studies on the chemical constituents of the South China Sea sponge Phacellia fusca
Corresponding Author
Long-Mei Zeng
Department of Chemistry, Zhongshan University, Guangzhou 510275
Long-Mei Zeng, Department of Chemistry, Zhongshan University, Guangzhou 510275
J. Francis Schmitz, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Dick van Der Helm, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorXiong Fu
Department of Chemistry, Zhongshan University, Guangzhou 510275
Search for more papers by this authorJing-Yu Su
Department of Chemistry, Zhongshan University, Guangzhou 510275
Search for more papers by this authorFlorecita De Guzman
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorCorresponding Author
J. Francis Schmitz
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Long-Mei Zeng, Department of Chemistry, Zhongshan University, Guangzhou 510275
J. Francis Schmitz, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Dick van Der Helm, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorM. Bilayet Hossain
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorCorresponding Author
Dick van Der Helm
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Long-Mei Zeng, Department of Chemistry, Zhongshan University, Guangzhou 510275
J. Francis Schmitz, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Dick van Der Helm, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorCorresponding Author
Long-Mei Zeng
Department of Chemistry, Zhongshan University, Guangzhou 510275
Long-Mei Zeng, Department of Chemistry, Zhongshan University, Guangzhou 510275
J. Francis Schmitz, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Dick van Der Helm, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorXiong Fu
Department of Chemistry, Zhongshan University, Guangzhou 510275
Search for more papers by this authorJing-Yu Su
Department of Chemistry, Zhongshan University, Guangzhou 510275
Search for more papers by this authorFlorecita De Guzman
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorCorresponding Author
J. Francis Schmitz
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Long-Mei Zeng, Department of Chemistry, Zhongshan University, Guangzhou 510275
J. Francis Schmitz, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Dick van Der Helm, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorM. Bilayet Hossain
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorCorresponding Author
Dick van Der Helm
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Long-Mei Zeng, Department of Chemistry, Zhongshan University, Guangzhou 510275
J. Francis Schmitz, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Dick van Der Helm, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019–0370, U.S.A.
Search for more papers by this authorAbstract
Three pyrrololactam alkaloids have been isolated from the marine sponge Phacellia fusca Schmidt collected from the South China Sea, and their structures were determined as 1–3, on the grounds of spectral data. This is the first report of these compounds from this sponge. The structure of 1 was confirmed by X-ray analysis.
References
- 1 Schmitz, F.J., Gunasekera, S.P., Lakshmi, V., Tillekeratne, L.M.V., J. Nat. Prod., 48, 47 (1985).
- 2 Sharma, G.M., Buyer, J.S., Pomerantz, M.W., J. Chem Soc., Chem. Commun. 435 (1980).
- 3 Bax, A., J. Magn. Reson., 57, 314 (1984).
- 4 De Nanteul, G., Ahond, A., Guilhem, J., Poupat, C., Tran Huu Dau, E., Potier, P., Pusset, M., Pusset, J., Laboute, P., Tetrahedron, 41, 6019 (1985).
- 5 Kitagawa, I., Kobayashi, M., Kitanaka, K., Kido, M., Kyogoku., Y., Chem. Pharm. Bull., 31, 2321 (1983).
- 6 Utkina, N.K., Fedoreev, S.A., Maksimov, O.B., Khim. Prir. Soedin, 535 (1984). Chem. Abstr., 102, 146334h (1985).
- 7 Garcia, E.E., Benjamin, L.E., Fryer, R.I., J. Chem. Soc., Chem. Commun, 78 (1973).
- 8a) Endo, N., Nakagawa, M., Hamamoto, Y., Ishihama, M., Pure Appl. Chem., 58, 387 (1986).
- 8b) Cimino, G., De Rosa, S., De Stefano, S., Mazzarella, L., Puliti, R., Sodano, G., Tetrahedron Lett. 23, 767 (1986).
- 9 Mattia, C.A., Mazzarella, L., Puliti, R., Acta Cryst., B38, 2513 (1982).
- 10 Ramachandran, G.N., Sasisekharan, V., Adv. Protein Chem., 23, 283 (1968).
- 11 Main, P., Fiske, S.J., Hull, S.E., Lessinger, L., Germain, G., Declerq, J.P., Woolfson, M.M., “ MULTAN 80, A System of Computer Programs for the Automatic Solution of Crystal Structures from X-ray Diffraction Data”, University of York, England, 1980.
- 12 Sheldrick, G.M., “ SHELX 76, Program for Crystal Structure Determination”, University of Cambridge, England, 1986.
