Preparative Organic Chemistry
ChemInform Abstract: A Dramatic Enhancing Effect of InBr3 Towards the Oxidative Sonogashira Cross-Coupling Reaction of 2-Ethynylanilines.
First published: 02 June 2016
Abstract
The addition of InBr3 to the oxidative Sonogashira reaction of aryl acetylenes (I) and (V) with silane (II) leads to a dramatic increase in reactivity to afford the corresponding 1,3-enynes (III) and (VI), respectively.
