ChemInform Abstract: Synthesis of 6-Amino-2,4-dihydropyrano[2,3-c]pyrazol-5-carbonitriles Catalyzed by Silica-Supported Tetramethylguanidine under Solvent-Free Conditions.
Abstract
The title compounds are obtained by an efficient and environmentally benign four-component, one-pot cyclocondensation reaction of ethyl acetoacetate, hydrazine hydrate, aldehydes, and malononitriles.