Cu(I)-Catalyzed Three-Component Coupling Protocol for the Synthesis of Quinoline Derivatives.
Abstract
For Abstract see ChemInform Abstract in Full Text.
ChemInform Abstract
A synthesis of various quinolines is achieved by Cu(I)-catalyzed three-component condensation of aromatic aldehydes, aromatic amines and terminal alkynes. However, in a number of cases, non-cyclized intermediate alkynes are isolated as minor or even the sole product.