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ChemInform Abstract: Synthesis, Antiviral and Cytostatic Activities, of Carbocyclic Nucleosides Incorporating a Modified Cyclopentane Ring. Part 4. Adenosine and Uridine Analogues.
First published: 20 May 2010
Abstract
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ChemInform Abstract
New carbocyclic nucleosides are prepared by mounting a purine [cf. (V), (VI), (VII)], 8-azapurine [cf. (VIII), (IX)] or pyrimidine [cf. (XII), (XIII)] on the amino group of the aminoalcohol (I). The products are evaluated as antiviral and antitumor agents. Only purine derivative (V) displays any cytostatic activity.
