ChemInform Abstract: Leishmanicidal Activity of Some Stilbenoids and Related Heterocyclic Compounds.
Abstract
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ChemInform Abstract
The in vitro leishmanicidal activity of some natural stilbenoids and some derivatives as well as some related condensed heterocyclic derivatives on cutaneous, mucocutaneous and visceral strains of Leishmania is evaluated. The presence of a piperidide moiety seems to be very important for the anti-leishmanicidal activity. The most potent and selective compound is the dihydrostilbene piperidide (III). Only a few compounds possessing other structures display some activities, e.g. (IV).
