Heterocyclic Compounds
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ChemInform Abstract: Transformation of 2,2-Dioxoisothiazolo[5,4,3-d,e]quinolines to Pyrrolo[4,3,2-d,e]quinolin-2(1H)-ones.
First published: 23 May 2010
Abstract
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ChemInform Abstract
Refluxing sultams (I) with a cyanide and following acidic hydrolysis results in formation of the pyrroloquinolinones (I) which can be transformed to tetrahydropyrroloquinolines (VI), backbones of marine alkaloids.
