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ChemInform Abstract: Construction of a Carbapenam Skeleton Using Palladium-Catalyzed Cyclization.
First published: 24 May 2010
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
β-Lactams (I) and (V) having propargylic carbonate and phosphate side chains undergo facile Pd-catalyzed cyclization to afford carbapenem derivatives. In the presence of a bidentate ligand such as dppf, the propargylic benzoate (Ia) gives a carbacepham (III) instead of a carbapenem.
