Volume 32, Issue 39
Natural Products
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ChemInform Abstract: Studies of Anti-MRSA Parenteral Cephalosporins. Part 4. A Novel Water-Soluble N-Phosphono Type Prodrug for Parenteral Administration.

Tomoyasu Ishikawa

Tomoyasu Ishikawa

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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Yutaka Nakayama

Yutaka Nakayama

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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Mitsumi Tomimoto

Mitsumi Tomimoto

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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Shin-ichi Niwa

Shin-ichi Niwa

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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Keiji Kamiyama

Keiji Kamiyama

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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Shohei Hashiguchi

Shohei Hashiguchi

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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Yuji Iizawa

Yuji Iizawa

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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Kenji Okonogi

Kenji Okonogi

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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Akio Miyake

Akio Miyake

Pharm. Res. Div., Takeda Chem. Ind. Ltd., Yodogawa, Osaka 532, Japan

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First published: 24 May 2010

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract

The N-phosphono type prodrug (X) shows water-solubility appropriate for a product intended for intravenous injection and in vivo anti-MRSA activity comparable to that of vancomycin.

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