ChemInform Abstract: A New Route to Hydrophobic Amino Acids Using Copper-Promoted Reactions of Serine-Derived Organozinc Reagents.
Abstract
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ChemInform Abstract
In continuation of earlier works, 6 novel hydrophobic amino acid derivatives such as (VII) and (VIII) are synthesized. The key step in this approach is the Cu-catalyzed reaction of the serine-derived zinc reagent (I) with different allyl electrophiles.