Volume 32, Issue 18
Heterocyclic Compounds
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ChemInform Abstract: Stereoselective Dihydropyrido(2,1-a)isoindolone Synthesis via Diastereodivergent Heck Cyclizations on Chiral 1,4-Dihydropyridines.

Christophe Pays

Christophe Pays

Lab. Chim. Org.-Elem., CNRS, Univ. P. et M. Curie, F-75252 Paris, Fr.

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Pierre Mangeney

Pierre Mangeney

Lab. Chim. Org.-Elem., CNRS, Univ. P. et M. Curie, F-75252 Paris, Fr.

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First published: 27 May 2010

Abstract

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ChemInform Abstract

Heck cyclization reaction of chiral 1,4-dihydropyridine (IV) using non-reductive or reductive reaction conditions allows the stereodivergent synthesis of dihydropyrido[2,1-a]isoindolones such as (VII), (VIII), and (IX).

chemical structure image

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