Preparative Organic Chemistry
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ChemInform Abstract: A Convenient Method for the Alkylation of Sulfamides Using Alkyl Bromides and Mitsunobu Betaine.
First published: 27 May 2010
Abstract
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ChemInform Abstract
Regioselective monoalkylation of the sulfonamide (I) is achieved with alkyl bromides under Mitsunobu conditions. The method is also useful for the N-glycosylation of carbohydrates.
