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ChemInform Abstract: Studies on Anti-MRSA Parenteral Cephalosporins. Part 1. Synthesis and Antibacterial Activity of 7β-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-hydroxyiminoacetamido] -3-(substituted imidazo[1,2-b]pyridazinium-1-yl)methyl-3-cephem-4-carboxylates and Related Compounds.
First published: 30 May 2010
Abstract
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ChemInform Abstract
Among the novel cephem carboxylate derivatives prepared, compound (Ic) shows an excellent balance of activity against methicillin-resistant Staphylococcus aureus and Gram-negative bacteria.
