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ChemInform Abstract: Efficient Enantioselective Synthesis of (R)-(-)-Carnitine from Glycerol.
First published: 30 May 2010
Abstract
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ChemInform Abstract
A convenient, high yielding enantioselective synthesis of (R)-(-)-carnitine (IV) starting from glycerol is reported. The chiral information is introduced into (I) by reaction with the Oppolzer chiral sulfonamide (II). The synthesis is applicable on a large scale process and the chiral auxiliary can be completely recovered.
