Volume 32, Issue 7
Preparative Organic Chemistry
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ChemInform Abstract: A Practical o-Hydroxybenzylamine-Promoted Enantioselective Addition of Dialkylzincs to Aldehydes with Asymmetric Amplification.

Gianni Palmieri

Gianni Palmieri

Dip. Sci. Chim., Univ. Camerino, I-62032 Camerino, Macerata, Italy

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First published: 30 May 2010

Abstract

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ChemInform Abstract

Among various title amines (I)-(III) tested, derivative (Ia) is found to be the most effective one. Under the optimized conditions shown, good to excellent enantioselectivities are observed for the desired alcohols.

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