ChemInform Abstract: Nickel(0)-Catalyzed Asymmetric Cross-Coupling Reactions of Allylic Compounds with Grignard Reagents Using Optically Active Oxazolinylferrocenylphosphines as Ligands.
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
The coupling reactions of allylic compounds bearing various leaving groups with aryl magnesium halides using Ni(acac)2 catalyst in the presence of title ligands [IPF or (XIV)] are studied. The efficiency of the ligands are examined for the reaction of methoxycyclohexene (Ic) with phenylmagnesium chloride. In all cases except for ligand (XIVa), a higher enantiomeric excess of product (III) is achieved than with a corresponding ligand only having central chirality. Ligand IPF leads to the highest enantiomeric excess.
