Heterocyclic Compounds
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ChemInform Abstract: A Facile KF/Al2O3-Mediated, Selective Alkylation of Benzodiazepin-2,5-diones.
First published: 07 June 2010
Abstract
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ChemInform Abstract
Benzodiazepin-2,5-diones (I) are highly selectively alkylated at the aniline nitrogen when alkyl halides (II) in the presence of KF on alumina are used. The use of a solid reagent makes the process suitable for the preparation of libraries.
