Heterocyclic Compounds
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ChemInform Abstract: The Synthesis of Substituted Pyridylpyrimidine Fungicides Using Palladium-Catalyzed Cross-Coupling Reactions.
First published: 07 June 2010
Abstract
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ChemInform Abstract
Cross-coupling of 2,6-dibromopyridine (I) with the 2-bromopyrimidines (II) gives the key compounds (III) in multi-gram quantities. Their cross-coupling with readily generated phenyl, pyridyl or benzyl zinc chlorides leads to substituted pyridylpyrimidine fungicides.
