ChemInform Abstract: Chiral Diphenylthiophosphoramides: A New Class of Chiral Ligands for the Silver(I)-Promoted Enantioselective Allylation of Aldehydes.
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
For the first time it is demonstrated that chiral phosphoryl sulfides catalyze the enantioselective allylation of aldehydes with tributylallyltin using Ag(I) salt. By means of the novel chiral thiophosphoramide TPA, under optimized conditions secondary (R)-alcohols are obtained with moderate enantioselectivities. Utilizing bis(thiophosphoramides) (VI) as chiral ligands, the enantioselectivities of alcohol (IIIa) reach only 9-15%.
