ChemInform Abstract: Synthesis of N-(Hydroxy)amide- and N-(Hydroxy)thioamide-Containing Peptides.
Abstract
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ChemInform Abstract
A new technology for the introduction of either N-hydroxyamide or N-(hydroxy)thioamide linkages into pseudopeptide chains without racemization involving the coupling of N-(benzoyloxy)amines with Fmoc-protected amino acid derivatives [→(III)] as the crucial step is developed.