Volume 31, Issue 23
Isocyclic Compounds
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ChemInform Abstract: Rapid Synthesis of 2-Cyanobenzothiazole, Isothiocyanate and Cyanoformanilide Derivatives of Dapsone.

Thierry Besson

Thierry Besson

Lab. Genie Proteique Cell., Chim. Org. Biocatal., Univ. La Rochelle, F-17042 La Rochelle, Fr.

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Jerome Guillard

Jerome Guillard

Lab. Genie Proteique Cell., Chim. Org. Biocatal., Univ. La Rochelle, F-17042 La Rochelle, Fr.

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Charles W. Rees

Charles W. Rees

Lab. Genie Proteique Cell., Chim. Org. Biocatal., Univ. La Rochelle, F-17042 La Rochelle, Fr.

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First published: 08 June 2010

Abstract

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ChemInform Abstract

Derivatives of the leprostatic drug dapsone (Ia) are prepared from imino-1,2,3-dithiazoles (III) which are readily available by condensation of bisamines, including dapsone, with Appel salt.

chemical structure image

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