Heterocyclic Compounds
Full Access
ChemInform Abstract: Synthesis and Biological Activity of N-(Aminoiminomethyl)-1H-indole Carboxamide Derivatives as Na+/H+ Exchanger Inhibitors.
First published: 09 June 2010
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
In order to get more information about the structure—activity relationships a variety of the title indole derivatives such as (III) and (V) are synthesized. The preparation of most of the starting materials is also described. Among all compounds the substance (Vd) is the most active one having an IC50 of 15 nM in a Na+/H+ exchange inhibitory test system.
