ChemInform Abstract: Dipeptides Containing D-Serine or D-Isoserine from the Same (R)-Aziridine-2-imide by a Simple Reversal of the Synthetic Procedure.
Abstract
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ChemInform Abstract
The regioselectivity of aziridine ring opening strongly depends on the presence or absence of the bulky imidazoline unit. Thus, starting from the derivative (III) the isoserine-containing dipeptide is formed, whereas the aziridine-2-ester (IX) leads to the serine-containing dipeptide.