ChemInform Abstract: DBU-MeOH Promoted One-Pot Stereoselective γ-Functionalization of 1,3-Dicarbonyls: Reactivity of β-Ketoamides Towards α,β-Unsaturated Aldehydes.
Abstract
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ChemInform Abstract
α,β-Unsaturated aldehydes undergo a stereoselective DBU-mediated one-pot γ-allylidenation with acrylic β-ketoamides to yield synthetically useful 1,2-adducts.