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ChemInform Abstract: Regioselective N1-Alkylation of Guanosine Derivatives Protected at N2 by an N,N-Dialkyl Amidine Group.
First published: 10 June 2010
Abstract
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ChemInform Abstract
Under Mitsunobu conditions or in the presence of electrophilic alkylating reagents, alkylation of guanosine derivatives (I) and (IV), protected by an N,N-dialkyl amidine at the exocyclic amino group, occurs selectively on nitrogen N1 of the purine base.
